… Seventy- twohour release formulation of the poorly soluble drug silybin based on porous
silica nanoparticles: in vitro release kinetics and in vitro/in vivo correlations in beagle …

… After oral administration in beagle dogs of drug entrapped in … Based on the analysis of drug
release profiles in vitro, the … synthesis of monodispersed Porous Silica Nanoparticles (PSNs) …

… is low due to poor water solubility. This study aimed to … sustained release of silymarin from
porous silica nanoparticles (… Our in vitro release study indicated that, unlike free SBN, which …

… SLM is characterized by poor water solubility (less than 0.05 … (nm), and rp is the pore size
of the membrane filter (nm). … of drug release based on the highest correlation coefficient (R 2 ) …

… BIO-C® (micronized silymarin formulation) possesses an … solubilize poorly soluble drugs
[19] or protect their pore-loaded drug … release kinetics and in vitro/in vivo correlations in beagle …

… of cell-based assays, adjusted by using empirical in vitro/in vivo … the in vivo absorption
from silybin meglumine hollow sphere … in vivo release from beagle dogs with in vitro release …

… complexity of silymarin registration as a veterinary drug. In … -induced liver disease in 16
beagles. SIL was administered 4 d … , taxifolin, and dehydrosilybin on ROS production in vitro in …

… of the medication (plant extract), wait for it to dissolve, then put it … of SRB adsorbed is negatively
correlated with the number of … -Hoon Kim, Sung-Yum Seo In vitro, in vivo and in silico anti-…

… preparation of a self-emulsifying drug delivery system. … system enhanced the solubility and
biological effect. Furthermore, our in … upon investigating the in vitro/in vivo correlations [64,65]. …

… porous calcium phosphate microparticles of silybin (Zhu et al… vitro release of 6-Gingerol
with increased desired solubility. … for the solubilization of drugs with poor water solubility, thus …